13 results
diagnosis algorithm anemia differential hemolytic intravascular rheumatology hemophagocytic hlh injury liver lymphohistiocytosis agglutinin antibody bacilliformis bartonella cirrhosis classification coagulation cold
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... usually IgM) (e.g. primary ... • Intrinsic RBC ... #Hemolytic #Intravascular ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Cold AIHA • Alloimmune ... elliptocytosis - RBC ... Diagnosis #Algorithm #Causes ... #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... ↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... #diagnosis #management ... #treatment #rheumatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Celiac disease • Autoimmune ... : Autoimmune hepatitis ... (hemolysis) • ... diagnosis #algorithm #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... biliary cholangitis ... steatosis • Autoimmune ... Diagnosis #Algorithm #hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... Viral infection, autoimmune ... Blood smear - RBC ... CLL (older) • Autoimmune ... #anemia #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
: • Treat primary ... cause • Correct ... hydration • RBC ... #treatment #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
assessment+++ Primary ... solid cancers • Autoimmune ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... lysis → severe hemolytic ... TREATMENT: ​• Acute ... Fever #diagnosis #management
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... Cirrhosis - Management ... survey disease #PBC ... #Primary #Biliary ... #Treatment #hepatology
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