63 results
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Red Blood Cell (RBC ... cell, Other RBC ... Howell-Jolly bodies #RBC ... Pathology #Hematology #Diagnosis ... #Dyspmorphic #BloodSmear
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
on the left Myeloblast ... Differential Diagnosis ... Even with normal WBC ... counts may delay diagnosis ... #differential #diagnosis
Hyperacute Hypoxemia - Workup and Management
Differential Diagnosis: Aspiration, Flash Pulmonary Edema, Mucous Plugging, Bronchospasm, Pulmonary Embolism,
Differential Diagnosis ... lung sliding) Diagnostics ... STAT Labs (BMP, CBC ... #Management #treatment ... #criticalcare
Peritonitis - Spontaneous vs Secondary vs Peritoneal Dialysis Associated Peritonitis
Spontaneous Bacterial Peritonitis
 • Cirrhosis (high SAAG)
PMN > 250 • Treatment ... cloudy effluent) 2) WBC ... > 100 WBC, >50% ... Positive Culture • Treatment ... Secondary #Peritoneal #diagnosis
SIRS, qSOFA and Sepsis Definitions
Systemic Inflammatory Response Syndrome - Present if 2 2 of the following
< 32 mmHg • WBC ... Definitions #severity #criticalcare ... #infection #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... if high risk if WBC ... opacities • Diagnosis ... Renal Failure Treatment ... QD until normal WBC
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Hemolytic Anemia 1) DIAGNOSE ... ↑ LDH • Anti-RBC ... Hemolytic #Anemia #diagnosis ... #management #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... • Lab values: WBC ... organ damage • Treatment ... Low calcium • Treatment ... Syndrome #TLS #diagnosis
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
- Differential Diagnosis ... Dehydration Shock Treatment ... #Differential #Diagnosis ... #criticalcare # ... algorithm #treatment
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
Sepsis - Diagnosis ... WBC > 12 K or < ... recognition and treatment ... Sepsis #Criteria #Diagnosis ... #QSOFA #SIRS #criticalcare