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management leukemia algorithm chronic differential monoclonal workup aplastic blood classification disorders erythematosus gammopathies hemeonc hodgkins lupus lymphoma markers mgus multiplemyeloma
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Lymphocytosis on CBC ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Disorders - Myelodysplastic ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... - B-cell ... Blood #Disorders #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... lymphoid organs When Cancer ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... Vmphocytosis on routine CBC ... Transformation to large cell ... uw_IMresidency #CLL ... #hematology #hemeonc
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - ... Allogeneic stem cell ... #Syndrome #MDS ... #treatment #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Syndromes (MDS) ... factor (GCSF) treatments ... treatment (examples ... #Syndromes #diagnosis ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
• Hypocellular myelodysplastic ... syndrome (MDS) ... Treatment: ... #oncology #hematology ... #diagnosis #management
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Cr >2 mg/dL or CC ... 40 ml/min A - Anemia ... marrow plasma cell ... , B and T cell lymphoproliferative ... #hematology #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
, breast CA - Hematologic ... - CBC may also ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
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