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diagnosis oncology differential workup algorithm causes chronic cll leukemia lymphocytic management arthritis cell classification dermatology disease hemeonc hodgkins laboratory lymphoma
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC ... @AmyChung #Blood ... #Disorders #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... • Rheumatic disorders ... Non malignant hematologic ... effect following treatment ... Iron deficiency anemia
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... of peripheral blood ... on the left Myeloblast ... cultures, including blood ... #CBC #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
decreased PLT count: CBC ... plateletcount), peripheral blood ... changes), high MCV anemia ... or if a primary hematologic ... Causes #Workup #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... Vmphocytosis on routine CBC ... transformation) Treatment ... AIHA, PRCA) • Treatment ... Leukemia #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... lymphoproliferative disorders ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... workup #oncology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... , breast CA - Hematologic ... - CBC may also ... neutrophils in the blood ... Treatment: - Systemic
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Workup: • Full Blood ... platelets - WBC ... Hodgkin Lymphoma Treatment ... classification #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
the presence of anemia ... Polyarthritis: • Blood ... : • Complete blood ... count (CBC) • ... metabolic or endocrine disorders
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Biopsy: Solitary disorder ... • No CRAB - no anemia ... • CBC + diff • ... Bone marrow Treatment ... Diagnosis #Workup #Hematology
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