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Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
hematuria (RBC casts ... dysmorphic RBCs in urine ... #Syndrome #Comparison ... #Algorithm #Nephrology ... #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
RBC casts in urine ... but in severe cases ... #Classification ... #Proteinuria #Nephrology ... #Diagnosis
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome == Nephrotic Syndrome == Onset - Insidious Edema - ++++ Blood
Red blood cell casts ... Red blood cell casts ... edgarvlermamd - Nephrology ... #Comparison #Table ... #Nephrology #Diagnosis
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic ... edgarvlermamd - Nephrology ... #Diagnosis #Nephrology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic ... #Urine #Microscopy ... #nephrology #interpretation ... #diagnosis
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE) SLE patient develops
Lupus Nephritis ... > 500 mg/d • Nephritic ... dysmorphic RBCs, RBC casts ... , WBC casts) especially ... #sle #nephrology
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Acute Interstitial Nephritis ... sterile pyuria, WBC casts ... proteinuria, granular casts ... #Interstitial #Nephritis ... AIN #Algorithm #nephrology
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • Red cell casts ... • White cell casts ... disease • Granular casts ... #nephrology #casts
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
EM) Haematuria/nephritis ... Haemolytic-uraemic syndrome Nephrotic ... glomerular #diseases #nephrology ... #pathology #comparison ... #table #diagnosis
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
blood cells on urine ... microscopy. ... RBCs and/or RBC casts ... • Hereditary nephritis ... and >3.5g/day (nephrotic
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