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rheumatology neurology symptoms behcet cerebritis cns common cord cryofibrinogenemia cvid erythematosus gca giantcell hypogammaglobulinemia immunodeficiency immunology lupus sjogrens sle spinal
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Fever, Arthralgia/arthritis ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... #management #treatment
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... ) Differential Diagnosis ... , AS Treatment: ... #diagnosis #management ... #signs #symptoms
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
processes: • Systemic ... cryoglobulins • Negative causes ... to medium-sized arteries ... Antiphospholipid syndrome ... hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... signs/sx of inflammation ... very remarkable w/differential ... Treatment of GCA ... #Management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... to 8 years Clinical ... DDX - Other causes ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
• Secondary form ... salivary ducts Clinical ... Arthralgia and Arthritis ... Adenocarcinoma Treatment ... Diagnosis #Management
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... • Symptoms and signs ... , Scleroderma, Systemic ... MCTD, Sjogren syndrome ... #algorithm
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