58 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
pain • Bulky lymphadenopathy ... -> AML: Blast crises ... AML (Acute Myeloid ... • Immature/Myeloblasts ... cutaneous plaques) AML
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
Causes of Diffuse ... and Localized Lymphadenopathy ... Differential Diagnosis Algorithm ... • Neoplastic (Leukemia ... #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Lymphadenopathy ... Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
large, immature myeloblasts ... acute myelogenous leukemia ... (AML) that is most ... #Clinical #Path ... Rods #AuerRods #AML
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Differential Diagnosis Algorithm ... Myeloid Leukemia ... (AML) • Chronic ... Differential #Diagnosis #Algorithm ... endocrinology #causes
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... features in most cases ... promyelocytic #leukemia ... #APL #APML #Pathology ... #Hematology #Clinical
Differential Diagnosis for Generalized Lymphadenopathy

Viral
• HIV 
• EBV 
• CMV 
• HBV 
• Dengue 
• Rubella
for Generalized Lymphadenopathy ... • Lymphoma • Leukemia ... #Generalized #Lymphadenopathy ... Differential #Diagnosis #Causes ... #Algorithm #Oncology
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
Prolymphocytes In our case ... T-prolymphocytic leukemia ... Acute Myeloid Leukemia ... (AML). ... Pathology #Microscopy #Clinical
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Orange or Hep C Clinical ... early symptoms • Lymphadenopathy ... Exam/Signs: • Lymphadenopathy ... Transform to DLBCL, PML
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Differential Diagnosis Algorithm ... Ovarian - Leukemia ... Lymphoma: NHL, CML ... Differential #Diagnosis #Algorithm ... #causes #endocrinology