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differential hematology management acidosis addisons algorithm allergy b12 causes classification coagulation cobalamin dic disseminated endocrinology eosinophilia erythematosus insufficiency intravascular lactate
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
- Differential Diagnosis ... • Eosinophilic Leukemia ... ), Heme malig (AML ... Hypersensitivity (DRESS, drug-induced ... Eosinophilic pneumonia, Adrenal
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
• Symptoms: Reduced ... Serum DHEAS Diagnosis ... sodium, potassium, AM ... /dL -> Primary AI ... endocrinology #diagnosis
Lactic Acidosis - Classification and Differential Diagnosis Type A Lactic Acidosis: Inadequate Oxygen Delivery • Anaerobic muscular
and Differential Diagnosis ... with underlying disease ... failure, Infection, Leukemia ... Pancreatitis, Renal ... syndrome, Thiamine deficiency
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... Bleeding (64%) • Renal ... • Severe Liver Disease ... thrombopoietin deficiency ... #Coagulation #diagnosis
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... malabsorption (d/t reduced ... to IBD, celiac disease ... level (< 200 pg/mL ... e.g. leukemia
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... • Prolidase deficiency ... Antihistone: Drug induced ... Hodgkin lymphoma and leukemia ... Erythematosus #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... • Hairy Cell Leukemia ... Myeloproliferative Disease ... or folic acid deficiency ... Myelodysplastic #Syndromes #diagnosis
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