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differential management rheumatology algorithm causes oncology clinical photo syndrome rash comparison disorders skinrash chronic lupus pathophysiology pruritus secondary sle table
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Neutrophils • Immature/Myeloblasts ... CLL -> Invade Skin ... #Hematology #Oncology ... #Diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - Differential Diagnosis ... Reactive: - Systemic ... Inflammatory • Systemic ... Algorithm #Causes #Hematology
Leukemic skin Infiltrate: Patient with known Acute Myelogenous Leukemia presented with diffuse bullous lesions (not shown). These
Leukemic skin Infiltrate ... Acute Myelogenous Leukemia ... presented with diffuse ... Clinical #Photo #Dermatology ... #Infiltrate #AML
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Generalized Differential Diagnosis ... Cholestatic liver disease ... • Lymphoma • Leukemia ... #generalized #dermatology ... #Differential #Diagnosis
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... skin disease, Pulmonary ... disease (~93-95% ... Autoantibodies #diagnosis ... #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... and knees • Diffuse ... (DcSSc; diffuse ... interstitial lung disease ... #diagnosis #signs
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Chronic Myelogenous Leukemia ... disorders • Celiac disease ... effect following treatment ... Algorithm #Causes #Hematology
Algorithm for Diagnosis of the Vesiculobullous Rash Febrile, Diffuse Distribution: - Varicella, Smallpox, Disseminated, Gonococcal,
Algorithm for Diagnosis ... Rash Febrile, Diffuse ... Hand Foot & Mouth Disease ... Afebrile Diffuse ... #Dermatology #Skin
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential Diagnosis ... • Lymphoma • Leukemia ... Inflammatory • Systemic ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
- Differential Diagnosis ... Congenital Diseases ... Cancer: • Leukemia ... : • Systemic lupus ... #Hematology
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