335 results
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
large, immature myeloblasts ... acute myelogenous leukemia
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
cells within the myeloblast ... Leukemoid reaction ... part automated differential ... Leukemoid Reaction ... D/D leukemia: increases
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... , CLL Acute leukemias ... Chronic leukemia ... Lymphoblastic Leukemia ... Neutrophils • Immature/Myeloblasts
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Lymphadenopathy - Differential ... Neoplastic: - Leukemia ... Lymphoblastic Leukemia ... Pancytopenia, WBC differential ... Lymphadenopathy #LAD #Differential
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Neutrophils - Differential ... Chronic myelogenous leukemia ... Polycythemia vera Acute Leukemia ... #Neutrophils #Differential
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
Lymphadenopathy - Differential ... • Neoplastic (Leukemia ... Lymphadenopathy #LAD #Differential
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Lymphoblastic Leukemia ... Acute Myeloid Leukemia ... Chronic Myeloid Leukemia ... Hyperuricemia #Differential
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... Chronic myeloid leukemia ... Acute myeloid leukemia ... Acute basophilic leukemia ... #Basophilia #Differential
Differential Diagnosis of Leukemoid Reaction

Retrospective review of 135 patients with WBC >25k:
 - 48% infection
 -
Differential Diagnosis ... of Leukemoid Reaction ... twitter.com/thame #Leukemoid ... #Reaction #Differential
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... Chronic Myeloid Leukemia ... Thrombocytosis #Differential