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aflp algorithm coagulation injury obstetrics pathophysiology pregnancy acute arterial ascites biliary bleeding bruising cholangitis cirrhosis deficiencies deficiency dic disease disseminated
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
hypersplenism and related thrombocytopenia ... g/dl (suggest hepatic ... Cirrhosis/acute hepatitis ... #Diagnosis #causes ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Vasculature • Hepatic ... Congestion/CHF • Hepatic ... #Diagnosis #Causes ... Acute #algorithm #hepatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Medications - Heparin ... ) • Advanced Liver ... Alcohol, Viral hepatitis ... promyelocytic leukemia ... #diagnosis #hematology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
: <5 mg/dL • Hepatic ... imaging: Hepatic ... if severe • Hepatic ... Disease #Pregnancy #hepatology ... #comparison #differential
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Hepatic congestionl ... - Fulminant hepatic ... - Massive hepatic ... #diagnosis #differential ... #hepatology #SAAG
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... dysfunction (25%) • Hepatic ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin ... #management #hematology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
acid metabolism products ... = nonspecific (nausea ... infiltration) Differential ... Hepatitis, Preeclampsia ... #Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Vascular Causes ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Diagnosis Framework ... Syndrome, Ischemic Liver ... Hyperhomocysteinemia - Heparin-induced ... thrombocytopenia ... pathophysiology #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... bile ducts Differential ... Viral hepatitis, ... malignancies, Hepatic ... #workup #hepatology
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