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workup management myelodysplastic pancytopenia chronic erythematosus gap globulin lupus lymphocytic myelodysplasia protein proteingap rheumatology secondary sle sweet systemic thrombocytopenia thrombocytosis
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Eosinophilic Leukemia ... Syndrome - Chronic ... Diagnosis #Causes ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology ... #Diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Anemia • Toxic ... Non-lmmune: • HELLP Syndrome ... #Diagnosis #Algorithm ... #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... (MD) - Diagnosis ... Myelodysplastic #Syndrome ... #MDS #Diagnosis ... Management #treatment #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis): • Acute ... malignancies • Anemia ... Myelodysplastic syndrome ... #Diagnosis #Causes ... #hematology #secondary
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Diagnosis Algorithm ... HLH syndrome 5. ... marrow failure syndrome ... #Diagnosis #Algorithm ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Diagnosis Algorithm ... HLH syndrome 5 ... marrow failure syndrome ... #Diagnosis #Algorithm ... #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... aplasia • ITP ... • Richter’s Syndrome ... syndrome • Smoldering ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Anemia • Aplastic ... Cell Leukemia ... blood count with differential ... #diagnosis #hematology ... #oncology
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