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diagnosis differential algorithm chronic cll dermatology diffuse effusions emergencies eosinophilia erythematosus gap globulin knee lad lupus lymphadenopathy lymphocytic management mds
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Reactive: - Systemic ... Inflammatory • Systemic ... Fatigue • Acute ... #Hematology #Oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... Causes: - Idiopathic ... , breast CA - Hematologic ... cancer such as ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Neutrophils • Immature/Myeloblasts ... • Tumor lysis syndrome ... lymphoid organs When Cancer ... #Hematology #Oncology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Lymphomas - Systemic ... Mastocytosis - Acute ... Hypereosinophilic Syndrome ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... transformation to acute ... leukemia Management ... Management #treatment #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... rendering the immune system ... ’s lymphoma or acute ... diagnosis #workup #oncology ... #hematology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... : Tumor Lysis Syndrome ... Hyperuricemia • Acute ... differential #diagnosis #cancer
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Causes of Knee Effusions ... Infection - Systemic ... - Acute rheumatic ... - Leukemia ... Knee #Effusions #causes
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Pleural effusions • Acute ... Hodgkin lymphoma and leukemia ... • Lung cancer ... • Cervical cancer
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
• Plasma cell leukemia ... changes (POEMS syndrome ... ovarian tumors, lung cancers ... : Lymphoma, Leukemia ... inflammation (acute
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