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lupus signs sle systemic vasculitis ana anemia antibodies antinuclear aplastic apml autoimmune behcet classification dermatology differentiation disease gout mds myelodysplasia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
bone pain, fever, joint ... Neutrophils • Immature/Myeloblasts ... • Tumor lysis syndrome ... #Hematology #Oncology ... #Diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... Demyelinating syndromes ... Glomerulonephritis Myositis ... #signs #symptoms ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Joint pain • Swan ... Induced Lupus: • Symptoms ... Hodgkin lymphoma and leukemia ... #Diagnosis #Rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
and pain of the joints ... cutis Diagnosis ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... , Sjögren Syndrome ... , Myositis, Mixed ... ANA #patterns #rheumatology ... #diagnosis #differential
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behcet disease) Differential ... tears, Ischemia, Leukemia ... , AS Treatment: ... #diagnosis #management ... #rheumatology #
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... : >3 symptoms, or ... initiation • Differential ... #management #hematology ... #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ischemia - Skin: erythematous ... vesicular eruption - Joints ... systemic lupus erythematosus ... Presentation - Systemic Symptoms ... #diagnosis #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
virus (EBV) • Leukemia ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... ischemia • Skin: Erythematous ... • Progressive symptoms ... Palpable purpura, joint ... #Diagnosis #Rheumatology
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