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differential hematology lupus sle autoimmune dermatology disease myopathy signs systemic vasculitis activation ana anemia antibodies antinuclear aplastic apml behcet calcium
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... Demyelinating syndromes ... Glomerulonephritis Myositis ... #signs #symptoms ... #diagnosis #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... anti-synthetase syndrome ... , and arthritis ... after 2 years of treatment ... #diagnosis #rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... shoulders Signs & Symptoms ... exam and imaging Treatment ... #diagnosis #management ... #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
bone pain, fever, joint ... Neutrophils • Immature/Myeloblasts ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Oncology #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Joint pain • Swan ... arthropathy • 90% joints ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... , Sjögren Syndrome ... , Myositis, Mixed ... ANA #patterns #rheumatology ... #diagnosis #differential
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
• Myalgia • Myositis ... systemic lupus erythematosus ... inclusion body myositis ... Atorvastatin Diagnosis ... #management #treatment
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... , AS Treatment: ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... Diagnosis: ... and lower jaw Treatment ... #Rheumatology # ... diagnosis #management
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
inflammation of the joints ... and pain of the joints ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
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