6 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy #thrombocytopenic ... #purpura #TTP #HemolyticUremicSyndrome ... #HUS #thrombocytopenia ... #Comparison #Diagnosis ... #Table #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... coagulation (DIC ... microangiopathy: Thrombotic thrombocytopenic ... uremic syndrome (HUS ... #anemia
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... transfusion • Thrombocytopenia ... DITMA) - MAHA + Thrombocytopenia ... coagulopathy - Thrombocytopenia ... anticoagulants - Thrombocytopenia
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... Pregnancy - TTP/HUS ... presents with coagulation ... Bloodman #Pregnancy #Thrombocytopenia ... diagnosis #table #comparison
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
inflammation • Thrombocytopenia ... Primary Causes: - Thrombocytopenia ... disease - DIC/TTP/HUS ... - Hemolytic anemia ... : • DIC, TTP/HUS
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Lymphocytes - T or B lineage ... ALL is of B-cell lineage ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... , thrombocytopenia