53 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Artifact (redo CBC ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Algorithm Decreased WBCs ... • Secondary (e.g ... Diagnosis #Algorithm #Causes ... #Hematology
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
cells within the myeloblast ... Mature WBC: 80- ... LEUCOCYTOSIS WBC ... -100,000 per (e.g ... the underlying cause
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
decreased PLT count: CBC ... function test, ANA (e.g ... disease), HBsAg/anti-HBc ... or if a primary hematologic ... #Workup #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... Iron Deficiency (Eg ... Causes: Chronic ... Other • e.g ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Increased Requirement (e.g ... Cells, Normal WBCs ... Diagnosis #Algorithm #Causes ... #Hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... count cause hyperviscosity ... • Lab values: WBC ... unless worrisome EKG ... diagnosis #management #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... (usually IgG) (e.g ... • Intrinsic RBC ... Extravascular #Causes ... differential #diagnosis #hematology
Pericarditis can be seen on EKG with diffuse ST elevations without reciprocal changes along with diffuse
can be seen on EKG ... First line treatment ... in refractory cases ... #Pericarditis #Cardiology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... diagnosis #management #treatment ... #rheumatology