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diagnosis management differential oncology algorithm lupus sle chronic cll dermatology erythematosus generalized lymphocytic pruritus secondary treatment antibody aplastic arteritis arthritis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Reactive: - Systemic ... Inflammatory • Systemic ... (Pancytopenia, WBC ... #Hematology #Oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Artifact (redo CBC ... Chronic Myelogenous Leukemia ... Iron deficiency anemia ... #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
DIAGNOSE AIHA • Anemia ... ↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... → Systematic screening ... management #treatment #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... decreased PLT count: CBC ... changes), high MCV anemia ... or if a primary hematologic ... #Workup #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... on the left Myeloblast ... Tissue damage • Leukemia ... likelihood of negative clinical ... #CBC #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
and Primary Causes ... renal failure/uremia ... Hyperthyroidism CBC ... • Lymphoma • Leukemia ... #generalized #dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Orange or Hep C Clinical ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... -> AML: Blast crises ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... #Hematology #Oncology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... RBC are produced ... Pancytopenia is a hematologic ... well as varying clinical ... These causes could
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... virus (EBV) • Leukemia ... • ↓ WBC • ↓ ... #oncology #hematology
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