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hematology causes algorithm bruising bleeding palpable rash thrombocytopenia anemia blanching bruise classification dic disseminated ecchymosis extravascular hematomas hemolysis hemolytic hemostasis
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... vasculitis) or disorders ... #Dermatology #Rash ... #Petechiae #Purpura ... #Ddxof
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... disorders, coagulation ... #Differential # ... Diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Diagnosis Algorithm ... Sequestration Disordered ... Platelet Function ... • Disseminated Intravascular ... #Causes #Hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Rash - Differential ... Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... Complete blood count coagulation ... #Causes #dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
coagulation (DIC ... thrombocytopenic purpura ... lymphoproliferative disorders ... #Causes #differential ... #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Manifestations of DIC: • Petechiae ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
are typical of coagulation ... lowest levels Platelet ... Diagnosis VWF ... ability to bind platelets ... VWF:RCo/VWF:Ag (differentiate
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
(disseminated intravascular ... coagulation) ... bypass Vascular disorders ... peds #pediatrics #diagnosis ... #differential #
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... Diagnosis Framework ... , disseminated intravascular ... coagulation, or ... #Diagnosis #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by bleeding (petechiae ... , or all three myeloid ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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