11 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... disorders, coagulation ... #Differential # ... Diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Diagnosis Algorithm ... Sequestration Disordered ... Platelet Function ... • Disseminated Intravascular ... #Causes #Hematology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... vasculitis) or disorders ... #Dermatology #Rash ... Palpable #Algorithm #Differential ... #Ddxof
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
coagulation (DIC ... thrombocytopenic purpura ... lymphoproliferative disorders ... #Causes #differential ... #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... Petechiae • Purpura ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
(disseminated intravascular ... coagulation) ... bypass Vascular disorders ... peds #pediatrics #diagnosis ... #differential #
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... lymphoma, multiple myeloma ... #Management #treatment ... #hematology #differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Diagnosis Algorithm ... Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... Complete blood count coagulation ... #Causes #dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... Diagnosis Framework ... , disseminated intravascular ... coagulation, or ... #Diagnosis #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... , or all three myeloid ... Disorders • Nutritional ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis