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diagnosis hematology causes algorithm bruising anemia bleeding palpable petechiae rash thrombocytopenia aafp agglutinin classification cold dic disease disseminated extravascular hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
coagulation (DIC ... thrombocytopenic purpura ... lymphoproliferative disorders ... #Hemolytic #Intravascular ... #Causes #differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... disorders, coagulation ... DIC/TTP/HUS - Hemolytic ... #Differential # ... #nonpalpable #dermatology
Algorithm for the outpatient management of thrombocytopenia. (DIC = disseminated intravascular coagulation; EDTA = ethylenediaminetetraacetic acid;
the outpatient management ... = disseminated intravascular ... coagulation; EDTA ... acid; HELLP = hemolysis ... enzymes, and low platelet
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Bleeding / Bruising - Differential ... Sequestration Disordered ... Platelet Function ... Connective Tissue Disorders ... • Disseminated Intravascular
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
erythrocytes from the intravascular ... vasculitis) or disorders ... #Diagnosis #Dermatology ... Palpable #Algorithm #Differential ... #Ddxof
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Non-immune - Haemolytic ... (disseminated intravascular ... coagulation) ... bypass Vascular disorders ... pediatrics #diagnosis #differential
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Petechiae • Purpura ... Findings in DIC: • Platelet ... causes #treatment #management ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Thrombocytopenic Purpura ... reflection of intravascular ... hemolysis Platelet ... and decreased platelet ... WBC count and differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... younger pts) Differential ... significance (MGUS), CLL, Myeloma ... the RBCs causing intravascular ... #anemia #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... Complete blood count coagulation ... Algorithm #Causes #dermatology
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