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diagnosis hematology causes algorithm bruising petechiae thrombocytopenia anemia bleeding rash aafp agglutinin blanching bruise cold dic disease disseminated ecchymosis hematomas
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
coagulation (DIC ... thrombocytopenic purpura ... hemoglobinuria (PNH) Extravascular ... #Hemolytic #Intravascular ... #Extravascular
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
erythrocytes from the intravascular ... to extravascular ... vasculitis) or disorders ... #Differential # ... Ddxof
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... disorders, coagulation ... PURPURA: Platelet ... DIC/TTP/HUS - Hemolytic ... #nonpalpable #dermatology
Algorithm for the outpatient management of thrombocytopenia. (DIC = disseminated intravascular coagulation; EDTA = ethylenediaminetetraacetic acid;
the outpatient management ... = disseminated intravascular ... coagulation; EDTA ... acid; HELLP = hemolysis ... enzymes, and low platelet
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Bleeding / Bruising - Differential ... Sequestration Disordered ... Platelet Function ... Connective Tissue Disorders ... • Disseminated Intravascular
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Non-immune - Haemolytic ... (disseminated intravascular ... coagulation) ... bypass Vascular disorders ... pediatrics #diagnosis #differential
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... • Palpable variants ... #Disseminated #Intravascular ... causes #treatment #management ... #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... Complete blood count coagulation ... Algorithm #Causes #dermatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Thrombocytopenic Purpura ... reflection of intravascular ... hemolysis Platelet ... and decreased platelet ... WBC count and differential
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
is usually palpable ... of blood in the extravascular ... are typical of coagulation ... lowest levels Platelet ... VWF:RCo/VWF:Ag (differentiate
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