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diagnosis causes hematology algorithm petechiae bruising rash aafp anemia blanching bleeding bruise dic disseminated ecchymosis hematomas hemolysis nonpalpable outpatient pediatrics
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
vs Extravascular ... coagulation (DIC ... purpura (TTP), ... hemoglobinuria (PNH) Extravascular ... #Hemolytic #Intravascular
Algorithm for the outpatient management of thrombocytopenia. (DIC = disseminated intravascular coagulation; EDTA = ethylenediaminetetraacetic acid;
the outpatient management ... = disseminated intravascular ... coagulation; EDTA ... enzymes, and low platelet ... purpura.)
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
erythrocytes from the intravascular ... to extravascular ... vasculitis) or disorders ... #Differential # ... Ddxof
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... disorders, coagulation ... PURPURA: Platelet ... DIC/TTP/HUS - Hemolytic ... #nonpalpable #dermatology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Non-immune - Haemolytic ... (disseminated intravascular ... coagulation) ... bypass Vascular disorders ... pediatrics #diagnosis #differential
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Bleeding / Bruising - Differential ... Diagnosis Algorithm Thrombocytopenia ... Sequestration Disordered ... Platelet Function ... • Disseminated Intravascular
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... • Palpable variants ... #Disseminated #Intravascular ... causes #treatment #management ... #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
hemostasis: - Thrombocytopenia ... - Abnormal platelet ... Vasculitis - Collagen disorders ... Complete blood count coagulation ... Algorithm #Causes #dermatology
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
is usually palpable ... of blood in the extravascular ... are typical of coagulation ... lowest levels Platelet ... VWF:RCo/VWF:Ag (differentiate
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... reflection of intravascular ... hemolysis Platelet ... WBC count and differential
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