10 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): - Disseminated ... (DIC) - HELLP ... thrombocytopenic purpura ... lymphoproliferative disorders ... #Causes #differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... : Platelet Defects ... Fulminans (DIC ... #Differential # ... #nonpalpable #dermatology
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
meningococcemia, disseminated ... fulminans, disseminated ... intravascular coagulopathy ... (DIC), or TTP. ... #Diagnosis #Dermatology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
erythrocytes from the intravascular ... vasculitis) or disorders ... #Diagnosis #Dermatology ... Palpable #Algorithm #Differential ... #Ddxof
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Sequestration Disordered ... Platelet Function ... Deficiency • Disseminated ... Intravascular Coagulation
Algorithm for the outpatient management of thrombocytopenia. 
(DIC = disseminated intravascular coagulation; EDTA = ethylenediaminetetraacetic acid;
the outpatient management ... (DIC = disseminated ... intravascular coagulation ... enzymes, and low platelet ... #Diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... : • Platelet count ... #Disseminated # ... causes #treatment #management ... #hematology
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
- DIC (disseminated ... intravascular coagulation ... Congenital - Rare disorders ... bypass Vascular disorders ... pediatrics #diagnosis #differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... Meningococcemia - Disseminated ... fulminans - DIC ... Algorithm #Causes #dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... Qualitative defect in platelets ... characteristic of a platelet ... liver failure, disseminated ... intravascular coagulation