10 results
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
erythrocytes from the intravascular ... vasculitis) or disorders ... #Diagnosis #Dermatology ... Palpable #Algorithm #Differential ... #Ddxof
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): - Disseminated ... thrombocytopenic purpura ... lymphoproliferative disorders ... #Causes #differential ... #diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Sequestration Disordered ... Platelet Function ... Deficiency • Disseminated ... Intravascular Coagulation
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
- DIC (disseminated ... intravascular coagulation ... Congenital - Rare disorders ... bypass Vascular disorders ... pediatrics #diagnosis #differential
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... Petechiae • Purpura ... + Bleeding Treatment ... #Intravascular ... #management #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... lymphoma, multiple myeloma ... Syndrome #Diagnosis #Management ... #treatment #hematology ... #differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... Meningococcemia - Disseminated ... Algorithm #Causes #dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... Qualitative defect in platelets ... characteristic of a platelet ... liver failure, disseminated ... intravascular coagulation
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... , or all three myeloid ... Disorders • Nutritional ... blood count with differential ... Syndromes #diagnosis #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... - Low Hb and platelets ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... #oncology #management