Myeloid differential ddxof em endocrinology hypocalcemia causes calcium hypercalcemia pth elevated evaluation hyperparathyroidism levels

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Hypocalcemia Laboratory Evaluation

Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between

Hypocalcemia Laboratory ... Evaluation Serum ... levels of PTH, ... disorders causing hypocalcemia ... kidney disease #Hypocalcemia

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Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
• Primary Hyperparathyroidism
• Familial Hypocalciuric Hypercalcemia
Low

Hypercalcemia - ... Hypocalciuric Hypercalcemia ... Low PTH: • Elevated ... Thiazides/Lithium #Hypercalcemia ... #endocrinology

Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
• Adenoma
• Hyperplasia
• MEN 1 and 2A
Tertiary Hyperparathyroidism

Hypercalcemia - ... • Hypercalcemia ... Hypocalciuria Hypercalcemia ... Multiple Myeloma ... Paget's Disease #Hypercalcemia

Hypocalcemia - Differential Diagnosis Algorithm
• Low Serum Mg: GI losses, Renal losses, Alcoholism, Malnutrition, Drug-Induced

Hypocalcemia - Differential ... Level Elevated ... Level Inappropriately ... emoryimchiefs #Hypocalcemia ... #Differential #

Causes of Hypercalcemia
Parathyroid gland structure-related
• Primary hyperparathyroidism
• Parathyroid adenoma
• Parathyroid hyperplasia
• Parathyroid

Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... • Sarcoidosis (elevated ... Milk-alkali syndrome #Hypercalcemia ... #Causes #endocrinology

Hypercalcemia Evaluation
1) Clinical clues
- Is the patient symptomatic?
- Family history?
- Have you done

Hypercalcemia Evaluation ... 2) PTH - Frankly ... BrighamChiefs #Hypercalcemia ... #workup #differential ... #calcium #elevated

Causes of Hypocalcemia by Clinical Cause

Acute illness: pancreatitis, tumor lysis, severe illness - Secondary hyperparathyroidism from

Causes of Hypocalcemia ... levels Autoimmune ... Family history of hypocalcemia ... #Hypocalcemia ... #Causes #Differential

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Causes of Hypocalcemia - Differential Diagnosis
Decreased calcium absorption
• Vitamin D deficiency
-

Causes of Hypocalcemia ... - Differential ... resorption • Hypoparathyroidism ... Rhabdomyolysis #Hypocalcemia ... #endocrinology

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