Myeloid differential ddxof em endocrinology hypocalcemia causes calcium pth highcalcium workup evaluation diagnosis hyperparathyroidism

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Laboratory Evaluation of Hypocalcemia #Diagnosis #EM #IM #Evaluation #Workup #Hypocalcemia #PTH #Differential #Algorithm #Ddxof

of Hypocalcemia ... #Diagnosis #EM ... #Workup #Hypocalcemia ... #PTH #Differential ... #Algorithm #Ddxof

Hypocalcemia Laboratory Evaluation

Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between

Evaluation Serum ... levels of PTH, ... - Calcium-sensing ... #Diagnosis #Endocrinology ... #Differential

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Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
• Adenoma
• Hyperplasia
• MEN 1 and 2A
Tertiary Hyperparathyroidism

Differential Diagnosis ... Malignancy • PTH-Related ... Multiple Myeloma ... #Endocrinology ... #HighCalcium

Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for

Hypercalcemia Workup ... Determine whether PTH-dependent ... #Workup #Differential ... #endocrinology ... #calcium

Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
• Primary Hyperparathyroidism
• Familial Hypocalciuric Hypercalcemia
Low

Differential Diagnosis ... Algorithm Elevated PTH ... normal): • Primary Hyperparathyroidism ... Bony Mets - Calcium ... #causes #endocrinology

Hypercalcemia Evaluation
1) Clinical clues
- Is the patient symptomatic?
- Family history?
- Have you done

Hypercalcemia Evaluation ... 2) PTH - Frankly ... #workup #differential ... #diagnosis #endocrinology ... #evaluation #workup

Causes of Hypercalcemia
Parathyroid gland structure-related
• Primary hyperparathyroidism
• Parathyroid adenoma
• Parathyroid hyperplasia
• Parathyroid

Causes of Hypercalcemia ... Lithium use • Calcium-sensing ... malignancies • Multiple myeloma ... #Causes #endocrinology ... #diagnosis #differential

Causes of Hypocalcemia - Differential Diagnosis
Decreased calcium absorption
• Vitamin D deficiency
-

Causes of Hypocalcemia ... - Differential ... resorption • Hypoparathyroidism ... Diagnosis #Causes ... #endocrinology

Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or

Hypertension - Workup ... and Differential ... (when evaluation ... Vasculitis • Endocrinologic ... #causes #Differential

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