10 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin ... Cold Agglutinins ... significance (MGUS ... ), CLL, Myeloma ... hemolytic #anemia #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... ) - Differential ... nemaline myopathy Cutaneous-centered ... Diagnosis #hematology ... #oncology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... myelodysplastic syndrome • Myeloid ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
gangrenosum • Cutaneous ... anemia due to cold ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... (e.g. primary cold ... agglutin disease ... Extravascular #Causes #differential ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... Agglutination - Cold ... agglutinins disease ... #workup #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
disease: GI, neuro, cutaneous ... Diagnosis of B-Symptoms ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... activity • ↓ LAP ... violaceous, nontender cutaneous ... #Leukemia #Hematology ... #Oncology #Diagnosis
A quick infographic on the importance of sun protection and the various results of sun damage
wavelengths #causes #diagnosis ... #dermatology #skin ... Sunburns and risk of cutaneous ... non-melanoma skin cancer: clinical ... Cold Spring Harb
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
, or all three myeloid ... compounds, alcohol, lead ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology