10 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Diagnosis Algorithm ... • Small Bowel Disorder ... Formation • Multiple Myeloma ... #Diagnosis #Algorithm ... #Causes #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm ... anemia - ... bcr-able (-) - Polycythemia ... #hematology #Markers ... Diagnosis #Algorithm
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
(sometimes) Macrocytic ... Unstable hemoglobin disorders ... lymphoma, Multiple myeloma ... #Morphology #differential ... #diagnosis #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Infections Macrocytic ... Non-megaloblastic: Liver ... Diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Lead poisoning • Macrocytic ... PD deficiency, Pulmonary ... Morphology #Atlas #key #diagnosis ... #differential # ... hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Diagnosis Algorithm ... • Rheumatic disorders ... Iron deficiency anemia ... #Diagnosis #Algorithm ... #Causes #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
anemia • Cold ... Blood smear - RBC ... younger pts) Differential ... significance (MGUS), CLL, Myeloma ... #hematology #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... Agglutination - Cold agglutinins ... membrane disorder ... Diagnosis #Algorithm ... #workup #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... changes), high MCV anemia ... ITP, unexplained pancytopenia ... #Workup #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Connective tissue disorders ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology