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rheumatology aortitis cryoglobulinemia cryoglobulins cutaneous dermatologic dermpath granulomatosis joint lesions leukemia lupus management manifestations mycobacteria nontuberculous ntm pathology polyangiitis polychondritis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Sarcoidosis • GPA ... #dermatology ... #joint #pain #skin ... #rashes #differential ... #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA ... GPA causes disease ... Diagnosis: Vasculitis ... #dermatology #rash ... #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... Systemic lupus erythematosus ... (SLE), Sarcoidosis ... : Cancer, Histiocytic ... #Diagnosis #rheumatology
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
disease (10%) : SLE ... (5%): PAN > GPA ... cancers/hemopathies ... (3%) • Infections ... #dermpath #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... lymphoid organs When Cancer ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
> PR3 60% • GPA ... mucositis - Rash ... • ANCA (Dx: GPA ... differential #diagnosis ... classification
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
- Protein Gap ( ... globulin gap (> ... gammopathy, and skin ... gastric tumors • Hematology ... #diagnosis #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... : • Clinical triad ... - GPA, EGPA, microscopic ... systemic lupus erythematosus ... #types #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Disease Classification ... rash • Erythematous ... fibromyalgia) • Infections ... Arthritis: • Joint pain ... #Diagnosis #Rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Causes: - Idiopathic ... Leukocytoclastic vasculitis ... #diagnosis #dermatology ... #oncology
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