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hematology causes algorithm anemia thrombocytosis blood classification hemolytic oncology product reactions agglutinin atlas bloodcell cold disease hyperkalemia lymphoma mcv mds
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - Differential ... Diagnosis Platelet ... blood loss (Fe deficiency ... Myelofibrosis • Chronic Myeloid ... #Platelets #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... with or without platelet ... #Anemia #Differential ... #workup #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... - Low Hb and platelets ... - WBC may be high ... Immunohistochemical studies (to differentiate ... #oncology #management
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... specifically: iron deficiency ... , hemolysis, hemorrhage ... MF) • Chronic myeloid ... #hematology #secondary
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Count - Differential ... Diagnosis Algorithm ... blood loss, Acute hemolysis ... , deficiency anemia ... #Differential #
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... Chronic Infection) High ... #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Microangiopathic Hemolytic ... lymphoma, Multiple myeloma ... lymphoma, Multiple myeloma ... RBC #Morphology #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... DIC/TTP/HUS - Hemolytic ... necrosis) • VIT K deficiency ... #Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... younger pts) Differential ... significance (MGUS), CLL, Myeloma ... • Symptoms: High ... #anemia #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
recipients w/ IgA deficiency ... common following platelet ... High mortality. ... #Transfusion #diagnosis ... #management #hematology
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