16 results
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Diagnosis Platelet ... Reactive: • Anemia/blood ... Non-infectious (malignancy, rheumatologic ... Myelofibrosis • Chronic Myeloid ... #Platelets #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Lymphoma - Comparison ... • Other hematologic ... #oncology #diagnosis ... #differential # ... hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... Disorders: • Chronic myeloid ... myeloid leukemia ... Colitis and Crohn’s Disease ... #hematology #basophils
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
- Low Hb and platelets ... Immunohistochemical studies (to differentiate ... number of sites of disease ... classification #hematology ... #oncology #management
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... Diagnosis Neurologic-Centered ... Ig deposition disease ... #Diagnosis #hematology ... #oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Disorders - Differential ... Diagnosis and Workup ... plateletcount), peripheral blood ... (CVID, WAS), (neurologic ... #Workup #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... • Neutrophils (myeloid ... Myeloid Leukemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
cells can indicate disease ... Lymphocytosis: Absolute blood ... ’s lymphoma or acute ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
, or all three myeloid ... Myeloproliferative Disease ... count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology