16 results
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Reactive: • Anemia ... /blood loss (Fe ... Myelofibrosis • Chronic Myeloid ... #Diagnosis #causes ... #Platelets #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... : • Chronic myeloid ... myeloid leukemia ... #Diagnosis #causes ... #hematology #basophils
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
malignancies • Anemia ... MF) • Chronic myeloid ... leukemia (CML) ... #Diagnosis #Causes ... #hematology #secondary
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Infectious: • Acute ... • Rheumatic disorders ... • Celiac disease ... Iron deficiency anemia ... #Causes #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Unstable hemoglobin disorders ... #Red #BloodCell ... RBC #Morphology #differential ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Normal Blood Smear ... • Small Bowel Disorder ... Formation • Multiple Myeloma ... #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Blood Loss ... • Acute Bleed - ... Disease • Marrow ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... (myeloid)↑ • Mature ... Myeloid Leukemia ... #Hematology #Oncology ... #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... Diagnosis #Causes ... #Workup #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
younger pts) Differential ... Diagnosis Monoclonal ... significance (MGUS), CLL, Myeloma ... sensitize red blood ... #hematology #diagnosis