10 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... Disorders: • Chronic myeloid ... myeloid leukemia ... #Diagnosis #causes ... #hematology #basophils
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... (myeloid)↑ • Mature ... Myeloid Leukemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
cells can indicate disease ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... or acute leukemia ... #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... promyelocytic leukemia ... ABO incompatible blood ... #causes #treatment ... #management #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full Blood ... Immunohistochemical studies (to differentiate ... number of sites of disease ... Treatment • Early ... #hematology #oncology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... with systemic disease ... Causes: - Idiopathic ... (malignancy), lymphoma ... #dermatology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Amyloidosis • Lymphoma ... gastric tumors • Hematology ... : Lymphoma, Leukemia ... Gap #ProteinGap #differential ... #diagnosis #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
, or all three myeloid ... Myeloproliferative Disease ... count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
gingivitis or gingival leukemic ... liver failure, disseminated ... discern these causes ... • Acute DIC • ... #Diagnosis #Hematology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
From Blood Cancer ... clonal evolution to acute ... myeloid leukemia ... median age at diagnosis ... #algorithm #hematology