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hematology oncology syndrome mds neurology algorithm anemia aplastic cancer cd4 common cvid gbs guillain hodgkins hypogammaglobulinemia icl idiopathic immunodeficiency immunology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis): • Acute infection ... vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... MF) • Chronic myeloid ... #Diagnosis #Causes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Diagnosis and Management ... Summary myelo ... risk-stratification • Risks: infection ... #Diagnosis #Management
Causes of Splenic Infarcts - Differential Diagnosis • Myeloid disorders: Myeloproliferative neoplasms (myelofibrosis, polycythemia vera, essential
Causes of Splenic ... Infarcts - Differential ... Diagnosis • Myeloid ... thrombocythemia), Myelodysplastic ... syndromes, Acute
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
, or all three myeloid ... Significance (IDUS) • Immune ... • Parvovirus infection ... blood count with differential ... #Syndromes #diagnosis
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... directed towards the myelin ... #Syndrome #diagnosis ... #management #neurology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
mutations) • Immune ... and petechiae Causes ... • Hypocellular myelodysplastic ... CMV) • Epstein-Barr ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
(specifically immune ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
chemotherapy) • Genetic syndromes ... lymphoma. aplasia/myelodysplasia ... ) • Infections ... #hematology #Differential ... #Causes #lymphocytopenia
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... albicans • Epstein Barr ... #Inflammatory #Syndrome ... #Differential # ... Diagnosis #Management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... mediated disease • Immune ... vaccination - Myelin ... #management #neurology ... #differential
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