11 results
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis): • Acute infection ... vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... MF) • Chronic myeloid ... #Diagnosis #Causes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... Summary myelo ... risk-stratification • Risks: infection ... #Diagnosis #Management ... #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
, or all three myeloid ... Most common cytopenia ... Significance (IDUS) • Immune ... #Syndromes #diagnosis ... #hematology #oncology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... directed towards the myelin ... Common organisms ... #Syndrome #diagnosis ... #management #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... CMV) • Epstein-Barr ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
(specifically immune ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
chemotherapy) • Genetic syndromes ... lymphoma. aplasia/myelodysplasia ... ) • Infections ... #hematology #Differential ... #Causes #lymphocytopenia
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection ... #management #hematology ... #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Erythema nodosum • Immune ... Immunohistochemical studies (to differentiate ... #hematology #oncology ... #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... albicans • Epstein Barr ... #Inflammatory #Syndrome ... #Differential # ... Diagnosis #Management