31 results
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
- Causes and Treatment ... Plasmapheresis - Multiple myeloma ... hyperleukocytosis (AML ... #Causes #Differential ... #Management
Priapism 

Secondary Causes:
Medications- intracavernosal injections, anticoagulants, PDE5 inhibitors, alpha blockers, methylphenidate, cocaine
Any hyperviscosity syndrome (SCD, leukemia,
Secondary Causes ... hyperviscosity syndrome ... SCD, leukemia, myeloma ... Priapism #Diagnosis #Management ... #Urology #Differential
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... • Neutrophils (myeloid ... : Blast crises ... (Acute Myeloid ... • Tumor lysis syndrome
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... - Differential ... Thrombocytosis): • Acute infection ... Myelodysplastic syndrome ... MF) • Chronic myeloid
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of ... reactions, hematoma, pulmonary ... miscellaneous causes ... #unconjugated #differential ... #causes
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection ... #management #hematology
Causes of Splenic Infarcts - Differential Diagnosis
 • Myeloid disorders: Myeloproliferative neoplasms (myelofibrosis, polycythemia vera, essential
Causes of Splenic ... Infarcts - Differential ... Diagnosis • Myeloid ... Myelodysplastic syndromes ... Antiphospholipid syndrome
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Summary myelo ... old, ~10,000 new cases ... risk-stratification • Risks: infection ... #treatment #hematology
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Chronic inflammation causes ... Most Common Causes ... • Mounier-Kuhn syndrome ... mycobacteria Treatment ... #differential #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... , or all three myeloid ... • Parvovirus infection ... factor (GCSF) treatments ... blood count with differential