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diagnosis neurology hepatology liver algorithm injury oncology rheumatology myelodysplastic nephrology treatment aki apml barre cerebritis chemistry cns crisis dermatology differentiation
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... ) Pathophysiology ... = nonspecific (nausea ... infiltration) Differential
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... Thrombocytosis): • Acute ... Myelodysplastic syndrome ... MF) • Chronic myeloid ... #hematology #secondary
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Summary myelo ( ... old, ~10,000 new cases ... transformation to acute ... #MDS #Diagnosis ... #hematology #oncology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... lymphoma, melanoma, myeloma ... • Gilbert's syndrome
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Mixed - Check Acute ... as neoplasm or amyloid ... • Gilbert's syndrome ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... osmolarity If cause ... Anti-GBM, Anti-ds-DNA ... myoglobin • Myeloma ... • Cardio-renal syndrome
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... obstruction, HELLP Syndrome ... - Sophia Hayes MD ... #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... - ACS, AKI, acute ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... , or all three myeloid ... blood count with differential ... #diagnosis #hematology
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