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diagnosis hemophagocytic lymphohistiocytosis oncology product reactions cerebritis cns coagulation dic disseminated encephalopathy erythematosus grading hepatic hepatology hodgkins intravascular lupus lymphoma
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... Phagocytosis of blood ... Drugs, Unknown cause ... #treatment #summary ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
trigger • Almost all ... or autoimmune disease ... for refractory disease ... #Treatment #management ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #rheumatology #
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
number of sites of disease ... scans and can also ... Hodgkin Lymphoma Treatment ... #hematology #oncology ... #management
Hepatic Encephalopathy - Diagnosis and Management Summary Definition: • Alteration in brain function manifested by neuropsychiatric symptoms
Summary Definition ... of neurologic/cognitive ... over course of disease ... Encephalopathy #Grading #Classification ... #treatment #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... • Severe Liver Disease ... #treatment #management ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
skin that are caused ... three myeloid hematopoiesis ... Out Secondary Causes ... Myeloproliferative Disease ... Syndromes #diagnosis #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
One Pager Summary ... donors (due to anti-HLA ... Presents as dyspnea ... Transfusions #diagnosis #management ... #hematology #reactions
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... Rule out other causes ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... donors (due to anti-HLA ... Presents as dyspnea ... Transfusion #diagnosis #management ... #hematology #reactions
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