7998 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... Syndrome: • Common Clinical ... vasculitis • Hematologic ... criteria for 1) hematologic ... peripheral blood myeloid
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
case of acute myeloid ... neutrophils #AML #Clinical ... #Hematology #Pathology
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk

#MultipleMyeloma
active multiple myeloma ... Oncology #HemeOnc #Hematology ... Hypercalcemia #Anemia #Clinical
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
other forms of myeloma ... rouleaux #formation #Clinical ... #Smear #Hematology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
whom there are no clinical ... concerning for myeloma ... diagnosis #management #hematology
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
Myeloma: In this ... #Myeloma #CD138 ... PlasmaCells #BoneMarrow #Clinical ... #Pathology #Hematology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Antibodies against myelin-associated ... glycoprotein (MAG) in myelin ... rituximab (in clinical ... Complications #diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... significance (MGUS), CLL, Myeloma ... hemolytic #anemia #hematology
Multiple Myeloma - Treatment Algorithm
a) Newly Diagnosed Myeloma: Transplant Eligible
b) Newly Diagnosed Myeloma: Transplant Ineligible

doi: 10.1038/s41408-020-00359-2

#Multiple
Multiple Myeloma ... Newly Diagnosed Myeloma ... Newly Diagnosed Myeloma ... -2 #Multiple #Myeloma ... Algorithm #management #hematology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Myelofibrosis • Chronic Myeloid ... causes #Platelets #hematology