11 results
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk

#MultipleMyeloma
Diagnosis of active ... multiple myeloma ... SLIMCRAB #Oncology #HemeOnc ... #Hematology #PlasmaCell ... Hypercalcemia #Anemia #Clinical
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... - Differential Diagnosis ... #Gammopathy #Clinical ... #Differential #Diagnosis ... #hematology #oncology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
patients with monoclonal ... whom there are no clinical ... concerning for myeloma ... Biopsy #algorithm #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... fludarabine) 3) Monoclonal ... #oncology #hematology ... #hemeonc #diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
MGUS • Multiple myeloma ... gastric tumors • Hematology ... : Lymphoma, Leukemia ... #differential #diagnosis ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... increase in gamma globulins ... #diagnosis #workup ... #oncology #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Monoclonal IgM ... significance (MGUS), CLL, Myeloma ... hemolytic #anemia #hematology ... #diagnosis
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Antibodies against myelin-associated ... glycoprotein (MAG) in myelin ... rituximab (in clinical ... Complications #diagnosis ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... virus (EBV) • Leukemia ... antithymocyte globulin ... Anemia #oncology #hematology ... #diagnosis #management
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
evolution to acute myeloid ... leukemia (AML). ... median age at diagnosis ... importance of clinical ... #algorithm #hematology