8 results
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
whom there are no clinical ... concerning for myeloma ... #MGUS #Biopsy # ... algorithm #diagnosis ... #management #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... Diagnosis Neurologic-Centered ... #Gammopathy #Clinical ... #Significance #MGUS ... #hematology #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... cancer for which ... to IgM multiple myeloma ... #Significance #hematology ... #diagnosis #oncology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS ... glycoprotein (MAG) in myelin ... rituximab (in clinical ... Complications #diagnosis ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... significance (MGUS ... ), CLL, Myeloma ... hemolytic #anemia #hematology ... #diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Gammopathy Include: • MGUS ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... #differential #diagnosis ... #hematology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
evolution to acute myeloid ... leukemia (AML). ... median age at diagnosis ... importance of clinical ... #algorithm #hematology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
plasmacytoma) Clinical ... tissue composed of monoclonal ... patients with EMD myeloma ... • Multiple myeloma ... #Workup #Hematology