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leukemia chronic cll differential myelodysplastic treatment activation agglutinin cancer cerebritis cold erythematosus gammopathy hemeonc hemolytic lupus macrophage mas mgus myelodysplasia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
(MD) - Diagnosis ... Summary myelo ( ... cytopenias (usually anemia ... #MDS #Diagnosis ... #hematology #oncology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... - Differential Diagnosis ... Neurologic-Centered ... Ig deposition disease ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... fludarabine) 3) Monoclonal ... #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Scleromyxedema (CNS ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Neutropenia, anemia ... Pure red cell aplasia ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... involvement • 30%: CNS ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... (CAS): - Due ... Viral Infection Clinical ... significance (MGUS), CLL, Myeloma ... #hematology #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... #neurology #rheumatology ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... nervous system (CNS ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
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