14 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
) - Differential ... Ig deposition disease ... #Differential # ... Diagnosis #hematology ... #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma ... and Monoclonal ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... POEMS (Sclerotic myeloma ... POEMS (Sclerotic myeloma ... #Monoclonal #Differential ... #Diagnosis #Oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
to IgM multiple myeloma ... progression to multiple myeloma ... to light-chain myeloma ... #Significance #hematology ... #diagnosis #oncology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS ... antibody - Early treatment ... deposition disease ... Complications #diagnosis ... #hematology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
tubulopathy • Monoclonal ... malignancies Treatment ... #AKI #Cancer #Oncology ... #Differential # ... Diagnosis #Classification
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
younger pts) Differential ... Diagnosis Monoclonal ... significance (MGUS ... ), CLL, Myeloma ... hemolytic #anemia #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... lymphoma, multiple myeloma ... thrombocythemia), Autoimmune disease ... #Management #treatment ... #hematology #differential
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... chemotherapy for low-risk disease ... fludarabine) 3) Monoclonal ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
artery aneurysms Diagnosis ... ) Differential Diagnosis ... Arthritis, AS Treatment ... : monoclonal TNF-aIpha ... signs #symptoms #rheumatology