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clinical disease mgus myelodysplastic acute agglutinin aki anemia behcet cancer chronic classification cll cold cutaneous dermatology gammopathies gammopathy gap hemolytic
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology ... #oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma ... and Monoclonal ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... • Myeloid hemopathy ... #differential # ... diagnosis #dermatology ... #oncology #clinical
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
tubulopathy • Monoclonal ... change disease • Hematologic ... #AKI #Cancer #Oncology ... #Differential # ... Diagnosis #Classification
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
POEMS (Sclerotic myeloma ... POEMS (Sclerotic myeloma ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
MGUS • Multiple myeloma ... Smoldering multiple myeloma ... changes (POEMS syndrome ... Gap #ProteinGap #differential ... #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... younger pts) Differential ... Diagnosis Monoclonal ... significance (MGUS), CLL, Myeloma ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Paraneoplastic phenomenon ... CLL Diagnosis ... increase in gamma globulins ... #workup #oncology ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behcet disease) Differential ... Diagnosis: • Genital ... inhibitors • Uveitis- Ophthalmology ... refractory disease : monoclonal ... signs #symptoms #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... , or all three myeloid ... blood count with differential ... #diagnosis #hematology ... #oncology
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