10 results
diagnosis oncology myeloma rheumatology syndrome treatment acquired algorithm als amyotrophic autoinflammatory bonemarrow cd138 cell clinical differential e1 electrophoresis gammopathies indications
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... thrombocytopenia, multiple ... myeloma, myelodysplastic ... conditions - multiple ... cells NEJM Review
Multiple Myeloma - Treatment Algorithm a) Newly Diagnosed Myeloma: Transplant Eligible b) Newly Diagnosed Myeloma: Transplant Ineligible doi: 10.1038/s41408-020-00359-2 #Multiple
Multiple Myeloma ... Newly Diagnosed Myeloma ... -020-00359-2 #Multiple ... #Algorithm #management ... #hematology #oncology
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... osteolytic lesions and pathologic ... #Myeloma #Diagnosis ... #Management #oncology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... e.g. lymphoma, multiple ... myeloma, Waldenstrom ... Syndrome #Diagnosis #Management ... #treatment #hematology
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
• Suspected multiple ... myeloma, Waldenström's ... myeloma is suspected ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma ... g/dl LLN B - Bony ... MGUS #diagnosis #hematology
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies). They're difficult to identify
Myeloma: In this ... #Myeloma #CD138 ... RussellBodies #Body ... BoneMarrow #Clinical #Pathology ... #Hematology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
amyotrophy with the pathologic ... brainstem and multiple ... Can involve any body ... neurology #diagnosis #management
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
anywhere in the body ... patients with EMD myeloma ... IFE, FLC assay Pathology ... • Multiple myeloma ... Diagnosis #Workup #Hematology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cartilage in the body ... syndrome, MDS & Multiple ... myeloma Complications ... Polychondritis #rheumatology ... #diagnosis #management
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