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rheumatology oncology syndrome differential algorithm disease myeloma neurology treatment anemia hodgkins lymphoma mgus monoclonal signs workup abnormal acquired agglutinin als
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... Syndrome: • Common Clinical ... vasculitis • Hematologic ... conditions - multiple ... cells NEJM Review
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... Summary Clinical ... osteolytic lesions and pathologic ... #Myeloma #Diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... portion of the body ... + Extranodal (Multiple ... throughout the body ... Differential Diagnosis
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
and Management ... e.g. lymphoma, multiple ... myeloma, Waldenstrom ... adsorption onto cancer cells ... #hematology #differential
Bone Lesion on X-Ray - Differential Diagnosis Algorithm Exostotic • Osteochondroma Asymptomatic &/or Non-Active Bone Scam •
- Differential Diagnosis ... Myeloma Benign ... malignant) • Giant Cell ... Constitutional Symptoms ... Ewing's Sarcoma #Bony
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
constitutional symptoms ... progress to IgM multiple ... myeloma Non-IgM ... progression to multiple ... #diagnosis #oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma ... g/dl LLN B - Bony ... marrow plasma cell ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies). They're difficult to identify
Myeloma: In this ... core, most plasma cells ... RussellBodies #Body ... PlasmaCells #BoneMarrow #Clinical ... #Pathology #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... malignancies - B-cell ... , Myeloma • Waldenström ... sensitize red blood cells ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
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