18 results
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
case of acute myeloid ... AML #Clinical #Hematology ... #Pathology #Smear
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... conditions - multiple myeloma ... peripheral blood myeloid ... cells NEJM Review
Multiple Myeloma - Treatment Algorithm
a) Newly Diagnosed Myeloma: Transplant Eligible
b) Newly Diagnosed Myeloma: Transplant Ineligible

doi: 10.1038/s41408-020-00359-2

#Multiple
Multiple Myeloma ... Newly Diagnosed Myeloma ... Newly Diagnosed Myeloma ... Treatment #Algorithm #management ... #hematology #oncology
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies).

They're difficult to identify
Myeloma: In this ... #Myeloma #CD138 ... #PlasmaCells #BoneMarrow ... #Clinical #Pathology ... #Hematology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
other forms of myeloma ... Clinical #Smear #Hematology ... #Pathology
Eyelid Melanoma - Despite conservative interventions, the stye had persisted and the skin had become noticeably
Eyelid Melanoma ... the left upper eyelid ... C) #Clinical #Pathology ... #Derm #Eyelid # ... Melanoma #Microscopy #NEJM
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... osteolytic lesions and pathologic ... #Multiple #Myeloma ... #Diagnosis #Management
Megaloblastic neutrophils in bone marrow.

So-called "giant bands" and "giant metamyelocytes" (blue circles) are 1.5-2 times the
#neutrophils #BoneMarrow ... #Smear #Hematology ... #Pathology #Clinical
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... lymphoma, multiple myeloma ... Syndrome #Diagnosis #Management ... #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... Summary myelo ... acute leukemia Management ... MDS #Diagnosis #Management ... #treatment #hematology