32 results
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
case of acute myeloid ... #neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... Features: POEMS, AL ... amyloid, Cryoglobulinemia ... #Significance #MGUS ... Differential #Diagnosis #hematology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
significance (MGUS ... 1.5 gm/dL) IgM MGUS ... , low-risk MGUS ... concerning for myeloma ... diagnosis #management #hematology
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
IgM #gammopathy #MGUS ... #Clinical #Pathology ... #Hematology #Smear
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... to IgM multiple myeloma ... , AL amyloidosis ... to light-chain myeloma ... #Significance #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute • Myloid ... (AML) - CD13, CD33 ... • Lymphoid (ALL ... CD3 Chronic • Myloid ... Blood #Disorders #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... (Chronic Myeloid ... • Neutrophils (myeloid ... (Acute Myeloid ... #Leukemia #Hematology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... conditions - multiple myeloma ... peripheral blood myeloid ... cells NEJM Review
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• MM • WM • MGUS ... • MGCSMGRS ... POEMS (Sclerotic myeloma ... POEMS (Sclerotic myeloma ... Paraproteinemias #Hematology