10 results
diagnosis monoclonal gammopathy oncology differential management agglutinin algorithm autoinflammatory biopsy cell cold complications crisis disease e1 maha microangiopathic microscopy multiplemyeloma
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS ... #Significance # ... MGUS #Differential ... #Diagnosis #hematology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
of undetermined significance ... (MGUS) A bone ... whom there are no clinical ... concerning for myeloma ... diagnosis #management #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic ... anemia. ... DIC is a clinical ... #anemia #Hematology ... #Pathology #Smear
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
of Undetermined Significance ... No evidence of anemia ... insufficiency, Anemia ... #Undetermined #Significance ... #hematology #diagnosis
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... Syndrome: • Common Clinical ... Abnormalities: macrocytic anemia ... cells NEJM Review ... Autoinflammatory #Somatic #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... anemia • Cold ... of undetermined significance ... (MGUS), CLL, Myeloma ... #anemia #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... POEMS (Sclerotic myeloma ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
of Undetermined Significance ... (MGUS) Fracture ... glycoprotein (MAG) in myelin ... rituximab (in clinical ... Complications #diagnosis #hematology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Crisis (SRC) Clinical ... microangiopathic hemolytic ... anemia (MAHA) ... rule out other pathology ... Renal #Crisis #rheumatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... • No CRAB - no anemia ... IFE, FLC assay Pathology ... • Multiple myeloma ... Diagnosis #Workup #Hematology
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